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FLT1

Gene

fms related receptor tyrosine kinase 1

Locus: gene with protein productLocation: 13q12.3

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asFLT · VEGFR1
View full nomenclature history (7)
Previous symbolsFLT
Alias symbolsVEGFR1
Previous namesfms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), fms-related tyrosine kinase 1, fms related tyrosine kinase 1
Alias namesvascular endothelial growth factor receptor 1, vascular permeability factor receptor

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

V-set domain containingI-set domain containingVEGF receptor tyrosine kinase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.