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FNTB

Gene

farnesyltransferase, CAAX box, subunit beta

HGNCHGNC:3785EnsemblENSG00000257365NCBI Gene2342
Locus: gene with protein productLocation: 14q23.3

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Protein farnesyltransferase subunit betaP49356

Protein · therapeutic target

Clinically validated target · 1 approved medicine against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asFPTB
View full nomenclature history (2)
Alias symbolsFPTB
Previous namesfarnesyltransferase, CAAX box, beta

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Carcinoma, Non-Small-Cell Lung
Leukemia, Myeloid, Acute
Hypertension, Portal

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Farnesyltransferase, CAAX box, subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2024-03-11.
Open TargetsGene–disease associations from the Open Targets Platform.