GABRG2

Gene

gamma-aminobutyric acid type A receptor subunit gamma2

HGNCHGNC:4087 EnsemblENSG00000113327 NCBI Gene2566

Locus: gene with protein productLocation: 5q34

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Gamma-aminobutyric acid receptor subunit gamma-2P18507

Protein · therapeutic target

Clinically validated target · 60 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

View full nomenclature history (2)

Previous namesgamma-aminobutyric acid (GABA) A receptor, gamma 2

Alias namesGABA(A) receptor, gamma 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Generalized epilepsy with febrile seizures-plus

Epilepsy, Absence

Epilepsy

Lennox-Gastaut syndrome

Sleep Initiation and Maintenance Disorders

Migraine Disorders

Major depressive disorder

Panic disorder

Anxiety Disorders

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Gamma-aminobutyric acid type A receptor subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2024-01-15.

Open TargetsGene–disease associations from the Open Targets Platform.