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GJA3

Gene

gap junction protein alpha 3

HGNCHGNC:4277EnsemblENSG00000121743NCBI Gene2700
Locus: gene with protein productLocation: 13q12.11

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCZP3 · CX46
View full nomenclature history (6)
Previous symbolsCZP3
Alias symbolsCX46
Previous namesgap junction protein, alpha 3, 46kDa (connexin 46), gap junction protein, alpha 3, 46kD (connexin 46), gap junction protein, alpha 3, 46kDa
Alias namesconnexin 46

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Posterior polar cataract
Early-onset non-syndromic cataract
Cataract
Colitis, Ulcerative

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Gap junction proteins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.