GPC3

Gene

glypican 3

HGNCHGNC:4451 EnsemblENSG00000147257 NCBI Gene2719

Locus: gene with protein productLocation: Xq26.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSDYS · OCI-5 · SGBS · SGBS1 · SGB · DGSX

View full nomenclature history (7)

Previous symbolsSDYS

Alias symbolsOCI-5, SGBS, SGBS1, SGB, DGSX

Alias namesglypican proteoglycan 3

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Wilms Tumor

COVID-19

Genetic Diseases, Inborn

Dengue

Thyroid gland papillary carcinoma

Carcinoma, Pancreatic Ductal

Pancreatic neuroendocrine tumor

Exocrine pancreatic carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Glypicans

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.