GREM2

Gene

gremlin 2, DAN family BMP antagonist

HGNCHGNC:17655 EnsemblENSG00000180875 NCBI Gene64388

Locus: gene with protein productLocation: 1q43

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPrdc · FLJ21195 · CKTSF1B2 · DAND3

View full nomenclature history (7)

Alias symbolsPrdc, FLJ21195, CKTSF1B2, DAND3

Previous namesgremlin 2, gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis)

Alias namesprotein related to DAN and cerberus

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Benign prostatic hyperplasia

Gastritis, Atrophic

Osteoarthritis

Osteoarthritis, Knee

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

DAN family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.