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GRM1

Gene

glutamate metabotropic receptor 1

HGNCHGNC:4593EnsemblENSG00000152822NCBI Gene2911
Locus: gene with protein productLocation: 6q24.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asGPRC1A · mGlu1 · MGLUR1 · PPP1R85
View full nomenclature history (6)
Alias symbolsGPRC1A, mGlu1, MGLUR1, PPP1R85
Previous namesglutamate receptor, metabotropic 1
Alias namesprotein phosphatase 1, regulatory subunit 85

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Cerebellar Ataxia
Fragile X Syndrome
Schizophrenia

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Glutamate metabotropic receptorsProtein phosphatase 1 regulatory subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.