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GTF2B

Gene

general transcription factor IIB

HGNCHGNC:4648EnsemblENSG00000137947NCBI Gene2959
Locus: gene with protein productLocation: 1p22.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTFIIB
View full nomenclature history (1)
Alias symbolsTFIIB

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

HIV Infections
Hypertension
Sleep Initiation and Maintenance Disorders
Essential Hypertension
Corneal Ulcer
Gout
Communicable Diseases
Cardiovascular Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

General transcription factors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.