HFM1

Gene

helicase for meiosis 1

HGNCHGNC:20193 EnsemblENSG00000162669 NCBI Gene164045

Locus: gene with protein productLocation: 1p22.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSEC63D1 · MER3 · FLJ39011 · FLJ36760

View full nomenclature history (7)

Previous symbolsSEC63D1

Alias symbolsMER3, FLJ39011, FLJ36760

Previous namesSEC63 domain containing 1, HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae), HFM1, ATP dependent DNA helicase homolog

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Primary Ovarian Insufficiency

Genetic non-acquired premature ovarian failure

Neurodegenerative Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2026-02-11.

Open TargetsGene–disease associations from the Open Targets Platform.