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IBTK

Gene

inhibitor of Bruton tyrosine kinase

HGNCHGNC:17853EnsemblENSG00000005700NCBI Gene25998
Locus: gene with protein productLocation: 6q14.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asBTKI · DKFZP564B116 · BTBD26
View full nomenclature history (5)
Previous symbolsBTKI
Alias symbolsDKFZP564B116, BTBD26
Previous namesinhibitor of Bruton agammaglobulinemia tyrosine kinase, Bruton agammaglobulinemia tyrosine kinase inhibitor

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Diabetes Mellitus
Metabolism, Inborn Errors
bone Paget's disease
Ovarian dysfunction
Familial prostate cancer
Prostatic Neoplasms
Coronary Artery Disease

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Ankyrin repeat domain containingBTB domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.