IFNAR2

Gene

interferon alpha and beta receptor subunit 2

HGNCHGNC:5433 EnsemblENSG00000159110 NCBI Gene3455

Locus: gene with protein productLocation: 21q22.11

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Interferon alpha/beta receptor 2P48551

Protein · therapeutic target

Clinically validated target · 11 approved medicines against this target

Member of “Receptor, Interferon alpha-beta” · 4 related family papers (context, not papers about this gene)

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asIFNABR

View full nomenclature history (5)

Previous symbolsIFNABR

Previous namesinterferon (alpha, beta and omega) receptor 2

Alias namesinterferon alpha/beta receptor 2, IFNalpha/beta receptor subunit 2, type I interferon receptor 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Interferon receptors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.