IL1RL1

Gene

interleukin 1 receptor like 1

HGNCHGNC:5998 EnsemblENSG00000115602 NCBI Gene9173

Locus: gene with protein productLocation: 2q12.1

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Interleukin-1 receptor-like 1Q01638

Protein · therapeutic target

Clinical-stage target · 1 candidate in clinical development

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asST2 · FIT-1 · ST2L · ST2V · DER4 · T1 · IL33R

View full nomenclature history (9)

Alias symbolsST2, FIT-1, ST2L, ST2V, DER4, T1, IL33R

Alias namessuppressor of tumorigenicity 2, homolog of mouse growth stimulation-expressed

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Asthma

Hypersensitivity

Rhinitis, Allergic

Childhood onset asthma

Respiratory Tract Diseases

Pulmonary Disease, Chronic Obstructive

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

I-set domain containingInterleukin receptorsTIR domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2026-03-26.

Open TargetsGene–disease associations from the Open Targets Platform.