IL33

Gene

interleukin 33

HGNCHGNC:16028 EnsemblENSG00000137033 NCBI Gene90865

Locus: gene with protein productLocation: 9p24.1

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Interleukin-33O95760

Protein · therapeutic target

Clinical-stage target · 3 candidates in clinical development

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC9orf26 · DVS27 · DKFZp586H0523 · NF-HEV · IL1F11

View full nomenclature history (9)

Previous symbolsC9orf26

Alias symbolsDVS27, DKFZp586H0523, NF-HEV, IL1F11

Previous nameschromosome 9 open reading frame 26 (NF-HEV)

Alias namesDVS27-related protein, nuclear factor for high endothelial venules, interleukin-1 family, member 11

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Asthma

Hypersensitivity

Rhinitis, Allergic

Respiratory Tract Diseases

Childhood onset asthma

Venous Thrombosis

Chronic rhinosinusitis

Nasal Polyps

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Interleukins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.