INTS6

Gene

integrator complex subunit 6

HGNCHGNC:14879 EnsemblENSG00000102786 NCBI Gene26512

Locus: gene with protein productLocation: 13q14.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asDDX26 · DICE1 · HDB · Notchl2 · DBI-1 · DDX26A · INT6

View full nomenclature history (8)

Previous symbolsDDX26

Alias symbolsDICE1, HDB, Notchl2, DBI-1, DDX26A, INT6

Previous namesDEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Diabetes, Gestational

Optic Neuritis

Lysosomal Storage Diseases

Autism Spectrum Disorder

Carcinoma, Hepatocellular

Prostate carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Integrator complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.