ITGAV

Gene

integrin subunit alpha V

HGNCHGNC:6150 EnsemblENSG00000138448 NCBI Gene3685

Locus: gene with protein productLocation: 2q32.1

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Integrin alpha-VP06756

Protein · therapeutic target

Clinically validated target · 1 approved medicine against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asVNRA · MSK8 · VTNR · CD51

View full nomenclature history (8)

Previous symbolsVNRA, MSK8, VTNR

Alias symbolsCD51

Previous namesintegrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51), antigen identified by monoclonal antibody L230, vitronectin receptor, integrin, alpha V

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Myocardial Infarction

Angina Pectoris

Inflammatory Bowel Diseases

Glioblastoma

Ischemic Stroke

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesIntegrin alpha subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.