Back to discover

ITIH3

Gene

inter-alpha-trypsin inhibitor heavy chain 3

HGNCHGNC:6168EnsemblENSG00000162267NCBI Gene3699
Locus: gene with protein productLocation: 3p21.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asH3P
View full nomenclature history (5)
Alias symbolsH3P
Previous namesinter-alpha (globulin) inhibitor, H3 polypeptide, inter-alpha (globulin) inhibitor H3
Alias namespre-alpha (globulin) inhibitor, H3 polypeptide, inter-alpha-trypsin inhibitor heavy chain H3

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Schizophrenia
Major depressive disorder
Bipolar Disorder
Autism Spectrum Disorder
Attention Deficit Disorder with Hyperactivity
Smoking initiation
Risk-taking behaviour
Anorexia Nervosa
Tourette's Syndrome

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Inter-alpha-trypsin inhibitor heavy chains

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.