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KCNA4

Gene

potassium voltage-gated channel subfamily A member 4

HGNCHGNC:6222EnsemblENSG00000182255NCBI Gene3739
Locus: gene with protein productLocation: 11p14.1

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Potassium voltage-gated channel subfamily A member 4P22459

Protein · therapeutic target

Clinically validated target · 5 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asKCNA4L · HPCN2 · Kv1.4 · HK1 · PCN2
View full nomenclature history (7)
Previous symbolsKCNA4L
Alias symbolsHPCN2, Kv1.4, HK1, PCN2
Previous namespotassium voltage-gated channel, shaker-related subfamily, member 4-like, potassium voltage-gated channel, shaker-related subfamily, member 4

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Multiple Sclerosis
Myasthenia Gravis
Lambert-Eaton Myasthenic Syndrome
Neurodegenerative Diseases
Alcohol drinking
Refractive Errors
Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Potassium voltage-gated channelsBTB domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.