KCNC3

Gene

potassium voltage-gated channel subfamily C member 3

HGNCHGNC:6235 EnsemblENSG00000131398 NCBI Gene3748

Locus: gene with protein productLocation: 19q13.33

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Voltage-gated potassium channel KCNC3Q14003

Protein · therapeutic target

Clinically validated target · 5 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSCA13 · Kv3.3

View full nomenclature history (5)

Previous symbolsSCA13

Alias symbolsKv3.3

Previous namespotassium voltage-gated channel, Shaw-related subfamily, member 3, spinocerebellar ataxia 13, potassium channel, voltage gated Shaw related subfamily C, member 3

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Cerebellar Ataxia

Neurodegenerative Diseases

Genetic Diseases, Inborn

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Potassium voltage-gated channelsBTB domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.