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KLF12

Gene

KLF transcription factor 12

HGNCHGNC:6346EnsemblENSG00000118922NCBI Gene11278
Locus: gene with protein productLocation: 13q22.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asAP-2rep · HSPC122 · AP2REP
View full nomenclature history (7)
Alias symbolsAP-2rep, HSPC122, AP2REP
Previous namesKruppel like factor 12
Alias namesKLF12 zinc finger transcriptional repressor, AP-2rep transcription factor, AP-2 repressor

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Atrial Fibrillation
Restless Legs Syndrome
Hypothyroidism
COVID-19
Hashimoto's Disease
Respiratory Tract Diseases
Schizophrenia
Asthma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Zinc fingers C2H2-typeKLF transcription factors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.
Open TargetsGene–disease associations from the Open Targets Platform.