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KMT2B

Gene

lysine methyltransferase 2B

HGNCHGNC:15840EnsemblENSG00000272333NCBI Gene9757
Locus: gene with protein productLocation: 19q13.12

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asKIAA0304 · MLL2 · TRX2 · HRX2 · WBP7 · MLL1B · MLL4 · CXXC10
View full nomenclature history (11)
Alias symbolsKIAA0304, MLL2, TRX2, HRX2, WBP7, MLL1B, MLL4, CXXC10
Previous nameslysine (K)-specific methyltransferase 2B
Alias namesmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 4, Histone-lysine N-methyltransferase 2B

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Genetic Diseases, Inborn
Dystonic Disorders
Neurodegenerative Diseases
Complex neurodevelopmental disorder

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

PHD finger proteinsZinc fingers CXXC-typeHistone lysine methyltransferasesSET domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.