LAT2

Gene

linker for activation of T cells family member 2

HGNCHGNC:12749 EnsemblENSG00000086730 NCBI Gene7462

Locus: gene with protein productLocation: 7q11.23

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asWBSCR15 · WBSCR5 · WSCR5 · HSPC046 · LAB · NTAL

View full nomenclature history (12)

Previous symbolsWBSCR15, WBSCR5

Alias symbolsWSCR5, HSPC046, LAB, NTAL

Previous nameslinker for activation of T cells family, member 2, Williams-Beuren syndrome chromosome region 5, linker for activation of T-cells family member 2

Alias nameslinker for activation of B cells, non-T cell activation linker, linker for activation of T cells, transmembrane adaptor 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Lupus Erythematosus, Systemic

Pancreatic Neoplasms

Leukemia, Myeloid, Acute

Neoplasms

Acute promyelocytic leukemia

Arthritis, Rheumatoid

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.