LETM1

Gene

leucine zipper and EF-hand containing transmembrane protein 1

HGNCHGNC:6556 EnsemblENSG00000168924 NCBI Gene3954

Locus: gene with protein productLocation: 4p16.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSLC55A1 · Mdm38

View full nomenclature history (3)

Alias symbolsSLC55A1, Mdm38

Alias namesMdm38 homolog (yeast)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Respiratory Tract Infections

Alcohol drinking

Seasonal allergic rhinitis

Genetic Diseases, Inborn

Neurodevelopmental Disorders

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

EF-hand domain containingSolute carrier family 55, LETM mitochondrial cation/proton exchangers

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-27.

Open TargetsGene–disease associations from the Open Targets Platform.