Back to discover

LILRB1

Gene

leukocyte immunoglobulin like receptor B1

HGNCHGNC:6605EnsemblENSG00000104972NCBI Gene10859
Locus: gene with protein productLocation: 19q13.42

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Leukocyte immunoglobulin-like receptor subfamily B member 1Q8NHL6

Protein · therapeutic target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asLIR-1 · ILT2 · MIR-7 · CD85 · LIR1 · CD85j · PIRB · PIR-B
View full nomenclature history (11)
Alias symbolsLIR-1, ILT2, MIR-7, CD85, LIR1, CD85j, PIRB, PIR-B
Previous namesleukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
Alias namesmyeloid inhibitory receptor 7, leucocyte Ig-like receptor B1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Epstein-Barr Virus Infections
Miyoshi myopathy
Neoplasms
Stomach Neoplasms
Arthritis, Rheumatoid
Lupus Erythematosus, Systemic
Leukemia, Myeloid, Acute
Glioblastoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesInhibitory leukocyte immunoglobulin like receptors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.