LRIG1

Gene

leucine rich repeats and immunoglobulin like domains 1

HGNCHGNC:17360 EnsemblENSG00000144749 NCBI Gene26018

Locus: gene with protein productLocation: 3p14.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asLIG-1 · DKFZP586O1624 · LIG1

View full nomenclature history (5)

Alias symbolsLIG-1, DKFZP586O1624, LIG1

Alias namesortholog of mouse integral membrane glycoprotein LIG-1, leucine-rich repeat protein LRIG1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Atrial Fibrillation

Hyperuricemia

Kidney Failure, Chronic

Central Nervous System Neoplasms

Glioma

Placental retention

Anemia

Diabetes Mellitus, Type 2

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

I-set domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.