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LRP5

Gene

LDL receptor related protein 5

HGNCHGNC:6697EnsemblENSG00000162337NCBI Gene4041
Locus: gene with protein productLocation: 11q13.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asLRP7 · OPPG · EVR1 · LR3 · BMND1 · HBM · OPS · OPTA1 · VBCH2 · EVR4
View full nomenclature history (13)
Previous symbolsLRP7, OPPG, EVR1
Alias symbolsLR3, BMND1, HBM, OPS, OPTA1, VBCH2, EVR4
Previous namesosteoporosis pseudoglioma syndrome, exudative vitreoretinopathy 1, low density lipoprotein receptor-related protein 5

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Osteoporosis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Low density lipoprotein receptors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.