LRRC3

Gene

leucine rich repeat containing 3

HGNCHGNC:14965 EnsemblENSG00000160233 NCBI Gene81543

Locus: gene with protein productLocation: 21q22.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC21orf102 · LRRC3DN · C21orf30 · DKFZP434C128

View full nomenclature history (8)

Previous symbolsC21orf102, LRRC3DN, C21orf30

Alias symbolsDKFZP434C128

Previous nameschromosome 21 open reading frame 102, LRRC3 downstream neighbor, chromosome 21 open reading frame 30, LRRC3 downstream neighbor (non-protein coding)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Liver Diseases

Intracranial Aneurysm

Atrial Fibrillation

Hepatolenticular Degeneration

Alzheimer's Disease

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.