LRSAM1

Gene

leucine rich repeat and sterile alpha motif containing 1

HGNCHGNC:25135 EnsemblENSG00000148356 NCBI Gene90678

Locus: gene with protein productLocation: 9q33.3-q34.11

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asFLJ31641 · CMT2P · RIFLE · TAL

View full nomenclature history (7)

Alias symbolsFLJ31641, CMT2P, RIFLE, TAL

Alias namesE3 ubiquitin-protein ligase LRSAM1, TSG 101-associated ligase, RING finger leucine repeat rich

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Genetic Diseases, Inborn

Charcot-Marie-Tooth Disease

Headache Disorders

Carcinoma, Hepatocellular

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Ring finger proteinsSterile alpha motif domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.