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LYPLA2

Gene

lysophospholipase 2

HGNCHGNC:6738EnsemblENSG00000011009NCBI Gene11313
Locus: gene with protein productLocation: 1p36.11

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asAPT-2 · APT2
View full nomenclature history (4)
Alias symbolsAPT-2, APT2
Previous nameslysophospholipase II
Alias namesacyl-protein thioesterase 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Melanoma
Carcinoma, Squamous Cell
Carcinoma, Hepatocellular
Neoplasms
Colonic Neoplasms
Colorectal Neoplasms
COVID-19

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Depalmitoylases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2025-05-01.
Open TargetsGene–disease associations from the Open Targets Platform.