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MAP3K20

Gene

mitogen-activated protein kinase kinase kinase 20

HGNCHGNC:17797EnsemblENSG00000091436NCBI Gene51776
Locus: gene with protein productLocation: 2q31.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMLTKalpha · MLTKbeta · ZAK · MLTK · MLK7 · MRK
View full nomenclature history (8)
Alias symbolsMLTKalpha, MLTKbeta, ZAK, MLTK, MLK7, MRK
Alias namesZAK1 homolog, leucine zipper and sterile-alpha motif kinase (Dictyostelium), mixed lineage kinase 7

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Congenital fiber-type disproportion myopathy
Smoking initiation
Alcohol drinking
Asthma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Mitogen-activated protein kinase kinase kinasesMixed lineage kinase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.