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MAPT

Gene

microtubule associated protein tau

HGNCHGNC:6893EnsemblENSG00000186868NCBI Gene4137
Locus: gene with protein productLocation: 17q21.31

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asDDPAC · MAPTL · MTBT1 · tau · PPND · FTDP-17 · MSTD · MTBT2 · FLJ31424 · MGC138549 · PPP1R103 · tau-40 · Tau-PHF6
View full nomenclature history (17)
Previous symbolsDDPAC, MAPTL
Alias symbolsMTBT1, tau, PPND, FTDP-17, MSTD, MTBT2, FLJ31424, MGC138549, PPP1R103, tau-40, Tau-PHF6
Alias namesG protein beta1/gamma2 subunit-interacting factor 1, microtubule-associated protein tau, isoform 4, protein phosphatase 1, regulatory subunit 103, Tau-derived paired helical filament hexapeptide

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Frontotemporal Dementia
Pick Disease of the Brain

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Protein phosphatase 1 regulatory subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.