Pick Disease of the Brain
Recent clinical, regulatory, research and industry developments relating to this disease.
Phosphorylated Tau in Alzheimer's Disease and Other Tauopathies.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
Clinical trials
The current development programme across all trial phases.
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Major themes3
- Alzheimer Disease1
- Pick Disease of the Brain1
- Tauopathies1
Leading journals1
- International journal of molecular sciences1
Leading researchers6
- Bisht J1
- Culberson J1
- Rawat P1
- Reddy PH1
- Sehar U1
- Selman A1
Affiliations (unnormalised)3
- College Human Sciences1
- Graduate School of Biomedical Sciences1
- Texas Tech University Health Sciences Center1
Reference
Authoritative identity, definition & identifiers.
A rare form of DEMENTIA that is sometimes familial. Clinical features include APHASIA; APRAXIA; CONFUSION; ANOMIA; memory loss; and personality deterioration. This pattern is consistent with the pathologic findings of circumscribed atrophy of the poles of the FRONTAL LOBE and TEMPORAL LOBE. Neuronal loss is maximal in the HIPPOCAMPUS, entorhinal cortex, and AMYGDALA. Some ballooned cortical neurons contain argentophylic (Pick) bodies. (From Brain Pathol 1998 Apr;8(2):339-54; Adams et al., Principles of Neurology, 6th ed, pp1057-9)
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.