STAM

Gene

signal transducing adaptor molecule

HGNCHGNC:11357 EnsemblENSG00000136738 NCBI Gene8027

Locus: gene with protein productLocation: 10p12.33

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSTAM1

View full nomenclature history (3)

Alias symbolsSTAM1

Previous namessignal transducing adaptor molecule (SH3 domain and ITAM motif) 1

Alias namesHSE1 homolog (S. cerevisiae)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Listeriosis

Pick Disease of the Brain

Prion Diseases

Huntington's Disease

Hereditary diffuse leukoencephalopathy with axonal spheroids and pigmented glia

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

ESCRT-0

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.