Back to discover

MASP2

Gene

MBL associated serine protease 2

HGNCHGNC:6902EnsemblENSG00000009724NCBI Gene10747
Locus: gene with protein productLocation: 1p36.22

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMASP1P1 · Map19 · sMAP · MAP-2
View full nomenclature history (9)
Previous symbolsMASP1P1
Alias symbolsMap19, sMAP, MAP-2
Previous namesmannan-binding lectin serine peptidase 1 pseudogene 1, mannan-binding lectin serine protease 2, mannan-binding lectin serine protease 1 pseudogene 1
Alias namesmannose-binding lectin-associated serine protease 2, mannose-binding lectin associated protein 19

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Amyotrophic Lateral Sclerosis
Motor Neuron Disease
COVID-19
Neurodegenerative Diseases
Frontotemporal Dementia

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Serine proteasesSushi domain containingComplement system activation components

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.