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MCCC2

Gene

methylcrotonyl-CoA carboxylase subunit 2

HGNCHGNC:6937EnsemblENSG00000131844NCBI Gene64087
Locus: gene with protein productLocation: 5q13.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMCCB · MCCCβ
View full nomenclature history (6)
Alias symbolsMCCB, MCCCβ
Previous namesmethylcrotonoyl-Coenzyme A carboxylase 2 (beta), methylcrotonoyl-CoA carboxylase 2
Alias namesmethylcrotonoyl-CoA carboxylase beta, 3-methylcrotonyl-CoA carboxylase non-biotin containing subunit

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Genetic Diseases, Inborn
Autism Spectrum Disorder
spinal muscular atrophy, type IV
Alzheimer's Disease
Lysosomal Storage Diseases
Multiple Sclerosis
Parkinson's Disease

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Methylcrotonyl-CoA carboxylase subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.