Back to discover

MECOM

Gene

MDS1 and EVI1 complex locus

HGNCHGNC:3498EnsemblENSG00000085276NCBI Gene2122
Locus: gene with protein productLocation: 3q26.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMDS1 · EVI1 · PRDM3 · MDS1-EVI1 · KMT8E
View full nomenclature history (8)
Previous symbolsMDS1, EVI1
Alias symbolsPRDM3, MDS1-EVI1, KMT8E
Previous namesmyelodysplasia syndrome 1, ecotropic viral integration site 1
Alias namesPR domain 3

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Hypertension
Glaucoma
Pre-Eclampsia
Glaucoma, Open-Angle
Asthma
Prostate carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Zinc fingers C2H2-typePR/SET domain familyPutative lysine methyltransferases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2024-11-07.
Open TargetsGene–disease associations from the Open Targets Platform.