MED1

Gene

mediator complex subunit 1

HGNCHGNC:9234 EnsemblENSG00000125686 NCBI Gene5469

Locus: gene with protein productLocation: 17q12

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTRIP2 · PPARGBP · PPARBP · PBP · TRAP220 · RB18A · DRIP230 · CRSP200 · CRSP1

View full nomenclature history (10)

Previous symbolsTRIP2, PPARGBP, PPARBP

Alias symbolsPBP, TRAP220, RB18A, DRIP230, CRSP200, CRSP1

Previous namesPPAR binding protein

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Lysosomal Storage Diseases

Alzheimer's Disease

Multiple Sclerosis

Autoimmune disorder of central nervous system

Parkinson's Disease

Asthma

Urinary bladder carcinoma

Familial prostate cancer

Prostatic Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Mediator complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.