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MED27

Gene

mediator complex subunit 27

HGNCHGNC:2377EnsemblENSG00000160563NCBI Gene9442
Locus: gene with protein productLocation: 9q34.13

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCRSP8 · TRAP37 · CRSP34 · MED3
View full nomenclature history (5)
Previous symbolsCRSP8
Alias symbolsTRAP37, CRSP34, MED3
Previous namescofactor required for Sp1 transcriptional activation, subunit 8, 34kDa

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Cataract
Epilepsy
Neurodegenerative Diseases
Smoking initiation

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Mediator complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.