MFHAS1

Gene

multifunctional ROCO family signaling regulator 1

HGNCHGNC:16982 EnsemblENSG00000147324 NCBI Gene9258

Locus: gene with protein productLocation: 8p23.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMASL1 · LRRC65

View full nomenclature history (5)

Alias symbolsMASL1, LRRC65

Previous namesmalignant fibrous histiocytoma amplified sequence 1

Alias namesleucine rich repeat containing 65, malignant fibrous histiocytoma-amplified sequences with leucine-rich tandem repeats 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Hypertension

Alcohol drinking

Risk-taking behaviour

Asthma

Endometriosis

Seasonal allergic rhinitis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

ROCO family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-10-25.

Open TargetsGene–disease associations from the Open Targets Platform.