MIB1

Gene

MIB E3 ubiquitin protein ligase 1

HGNCHGNC:21086 EnsemblENSG00000101752 NCBI Gene57534

Locus: gene with protein productLocation: 18q11.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMIB · DIP-1 · KIAA1323 · ZZANK2 · ZZZ6

View full nomenclature history (7)

Alias symbolsMIB, DIP-1, KIAA1323, ZZANK2, ZZZ6

Previous namesmindbomb homolog 1 (Drosophila)

Alias namesDAPK-interacting protein 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Left ventricular noncompaction

Musculoskeletal Diseases

Alzheimer's Disease

Genetic Diseases, Inborn

Familial hypertrophic cardiomyopathy

Diabetes Mellitus

Diabetes Mellitus, Type 2

Cardiomyopathy, Dilated

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Ring finger proteinsZinc fingers ZZ-typeAnkyrin repeat domain containingMicroRNA protein coding host genesCentriolar satellite proteins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.