MKLN1

Gene

muskelin 1

HGNCHGNC:7109 EnsemblENSG00000128585 NCBI Gene4289

Locus: gene with protein productLocation: 7q32.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTWA2

View full nomenclature history (2)

Alias symbolsTWA2

Previous namesmuskelin 1, intracellular mediator containing kelch motifs

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Aortic Valve Stenosis

Alopecia

Cutaneous melanoma

Myeloproliferative disorder

Hair color

Cardiomyopathy, Hypertrophic

Hypertension

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CTLH complex subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.