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MLX

Gene

MAX dimerization protein MLX

HGNCHGNC:11645EnsemblENSG00000108788NCBI Gene6945
Locus: gene with protein productLocation: 17q21.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTCFL4 · MAD7 · MXD7 · bHLHd13
View full nomenclature history (6)
Previous symbolsTCFL4
Alias symbolsMAD7, MXD7, bHLHd13
Previous namestranscription factor-like 4, MAX-like protein X

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
46,XX gonadal dysgenesis
Diabetes Mellitus, Type 2
Metabolic Syndrome
Coronary Artery Disease
Diabetes Mellitus
Schizophrenia
Osteosarcoma
Respiratory Tract Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Basic helix-loop-helix proteinsMAX dimerization proteins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.