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MSRB3

Gene

methionine sulfoxide reductase B3

HGNCHGNC:27375EnsemblENSG00000174099NCBI Gene253827
Locus: gene with protein productLocation: 12q14.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asDFNB74 · FLJ36866 · DKFZp686C1178
View full nomenclature history (4)
Previous symbolsDFNB74
Alias symbolsFLJ36866, DKFZp686C1178
Previous namesdeafness, autosomal recessive 74

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Hearing loss, autosomal recessive
Deafness
Atrial Fibrillation
Sleep Apnea Syndromes
Non-syndromic genetic deafness
Hearing Loss
Nonsyndromic genetic hearing loss
Sleep Apnea, Obstructive

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.