MYD88

Gene

MYD88 innate immune signal transduction adaptor

HGNCHGNC:7562 EnsemblENSG00000172936 NCBI Gene4615

Locus: gene with protein productLocation: 3p22.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

View full nomenclature history (3)

Previous namesmyeloid differentiation primary response gene (88), myeloid differentiation primary response 88

Alias namesTLR adaptor MYD88

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Leukemia, Lymphocytic, Chronic, B-Cell

Lymphoma, Large B-Cell, Diffuse

Leukemia, Lymphoid

Immunologic Deficiency Syndromes

Waldenstrom macroglobulinemia

Primary central nervous system lymphoma

B-cell non-Hodgkin's lymphoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

TIR domain containingMy-T-BRC complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.