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MYL4

Gene

myosin light chain 4

HGNCHGNC:7585EnsemblENSG00000198336NCBI Gene4635
Locus: gene with protein productLocation: 17q21.32

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Myosin light chain 4P12829

Protein · therapeutic target

Clinically validated target · 2 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asALC1 · AMLC · GT1 · PRO1957
View full nomenclature history (8)
Alias symbolsALC1, AMLC, GT1, PRO1957
Previous namesmyosin, light polypeptide 4, alkali; atrial, embryonic, myosin, light chain 4, alkali; atrial, embryonic
Alias namesmyosin, atrial/fetal muscle, light chain, atrial myosin light chain 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Atrial Fibrillation
Cardiomyopathy, Hypertrophic
Cardiovascular Diseases
Heart Failure
Cardiomyopathy, Dilated

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Myosin light chains, class 1

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.