MYLK2

Gene

myosin light chain kinase 2

HGNCHGNC:16243 EnsemblENSG00000101306 NCBI Gene85366

Locus: gene with protein productLocation: 20q11.21

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asskMLCK · KMLC · MLCK2

View full nomenclature history (5)

Alias symbolsskMLCK, KMLC, MLCK2

Previous namesmyosin light chain kinase 2, skeletal muscle

Alias namesskeletal muscle myosin light chain kinase

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Familial hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy 1

Cardiomyopathies

Rare familial disorder with hypertrophic cardiomyopathy

Cardiomyopathy, Hypertrophic

Tachycardia, Ventricular

Parkinson's Disease

Fabry Disease

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Myosin light chain kinase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.