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NDUFA8

Gene

NADH:ubiquinone oxidoreductase subunit A8

HGNCHGNC:7692EnsemblENSG00000119421NCBI Gene4702
Locus: gene with protein productLocation: 9q33.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPGIV · MGC793
View full nomenclature history (5)
Alias symbolsPGIV, MGC793
Previous namesNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8 (19kD, PGIV), NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
Alias namescomplex I PGIV subunit

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Diabetes Mellitus, Type 2
Parkinson's Disease
Neurodegenerative Diseases
Multiple Sclerosis
Alzheimer's Disease
Lysosomal Storage Diseases
Autoimmune disorder of central nervous system

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

NADH:ubiquinone oxidoreductase supernumerary subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.