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NECTIN1

Gene

nectin cell adhesion molecule 1

HGNCHGNC:9706EnsemblENSG00000110400NCBI Gene5818
Locus: gene with protein productLocation: 11q23.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asHVEC · ED4 · PVRL1 · PRR · PRR1 · PVRR1 · SK-12 · HIgR · CLPED1 · CD111 · OFC7 · Nectin-1
View full nomenclature history (14)
Previous symbolsHVEC, ED4, PVRL1
Alias symbolsPRR, PRR1, PVRR1, SK-12, HIgR, CLPED1, CD111, OFC7, Nectin-1
Previous namespoliovirus receptor-related 1 (herpesvirus entry mediator C)
Alias namesnectin

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Cleft Lip
Systemic Inflammatory Response Syndrome

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesV-set domain containingC2-set domain containingNectins and nectin-like molecules

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.
Open TargetsGene–disease associations from the Open Targets Platform.