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NKX2-5

Gene

NK2 homeobox 5

HGNCHGNC:2488EnsemblENSG00000183072NCBI Gene1482
Locus: gene with protein productLocation: 5q35.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCSX · NKX2E · CSX1 · NKX2.5 · NKX4-1
View full nomenclature history (8)
Previous symbolsCSX, NKX2E
Alias symbolsCSX1, NKX2.5, NKX4-1
Previous namesNK2 transcription factor related, locus 5 (Drosophila), cardiac-specific homeo box
Alias namestinman (Drosophila) homolog

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Atrial septal defect
Atrial Fibrillation

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

NKL subclass homeoboxes and pseudogenes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2024-01-15.
Open TargetsGene–disease associations from the Open Targets Platform.