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NOS1

Gene

nitric oxide synthase 1

HGNCHGNC:7872EnsemblENSG00000089250NCBI Gene4842
Locus: gene with protein productLocation: 12q24.22

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asNOS · nNOS
View full nomenclature history (3)
Previous symbolsNOS
Alias symbolsnNOS
Previous namesnitric oxide synthase 1 (neuronal)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Stress Disorders, Post-Traumatic
Pre-Eclampsia
Diabetes Mellitus, Type 2
Pneumonia, Viral
Spondylitis, Ankylosing
Myocardial Infarction
Major depressive disorder

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

PDZ domain containingFlavoproteinsNitric oxide synthase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.