NPRL3

Gene

NPR3 like, GATOR1 complex subunit

HGNCHGNC:14124 EnsemblENSG00000103148 NCBI Gene8131

Locus: gene with protein productLocation: 16p13.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC16orf35 · CGTHBA · RMD11 · NPR3 · MARE · HS-40

View full nomenclature history (10)

Previous symbolsC16orf35

Alias symbolsCGTHBA, RMD11, NPR3, MARE, HS-40

Previous nameschromosome 16 open reading frame 35, nitrogen permease regulator-like 3 (S. cerevisiae), NPR3-like, GATOR1 complex subunit

Alias namesconserved gene telomeric to alpha globin cluster

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Familial focal epilepsy with variable foci

Genetic Diseases, Inborn

Neurodegenerative Diseases

Epilepsies, Partial

Epilepsy

Anemia, Sickle Cell

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

GATOR1 subcomplex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.